Horizon Scanning Technology Horizon Scanning Report Intraoperative ultrasound for breast lesion localisation during breast conserving surgery (lumpectomy)

Ultrasound-guided boost irradiation of tumor cavity after lumpectomy in breast cancer

Background:  After breast conserving surgery, most recurrences occur around the primary tumor site. This justifies the use of boost radiotherapy to the primary site of tumor. Surgical scar is not always a good surrogate for the location of the lumpectomy cavity. The aim of this study was to evaluate ultrasonic guidance for detection of the lumpectomy cavity after breast conserving surgery ...

Intraoperative ultrasound reduces the need for re-excision in breast-conserving surgery

BACKGROUND The purpose of this study was to evaluate ultrasound-guided surgery for palpable breast cancer by comparing the standard palpation-guided surgery in terms of the extent of healthy breast tissue resection, the percentage of tumor-free margins, and cosmetic outcomes. METHODS This was a prospective, observational cohort study conducted from January 2009 to July 2011. Breast cancer pat...

Horizon Scanning Technology Prioritising Summary Update Breast cancer diagnosis using ultrasound elasticity imaging

Surgical margins in breast-conserving therapy

Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-conserving therapy (BCT) for early-stage breast cancer. The majority of studies report positive resection margins in 20% to 40% of the patients who underwent BCT. This may result in an increased local recurrence (LR) rate or additional surgery and, consequently, adverse effects on cosmesis, psychological di...

Light-guided lumpectomy: device and case report.

We describe the development, design, fabrication, and testing of an optical wire to assist in the surgical removal of small lesions during breast-conserving surgery. We modify a standard localization wire by adding a 200-μm optical fiber alongside it; the resulting optical wire fit through an 18 gauge needle for insertion in the breast. The optical wire is anchored in the lesion by a radiologis...